Adds 'leftsovers' to the segment frame after re-inserting small segments.

Iterates over the segments frame and if the space between adjacent segments is greater than one, then we use GRanges to obtain genomic data from this missing region in the data frame. We update the adjacent segment's start or end positions depending on which segment is closer to the missing segment.

Do this as long as adjacent segments are in the same chromosome arm.

Usage

CorrectLeftovers(segments, granges_obj)

Arguments

segments

A data frame. Segments with size >= 3Mb.

granges_obj

A GRanges object: is used as reference to check whenever we have empty space between segments and get the ratio_median of this missing portion.